Connect to Salesforce APIs to Interact with Marketing Cloud
How you connect an API depends on which API you plan to use. To use REST-based APIs, including REST API, Bulk API 2.0, and Data 360 Connect API, create an external client app with the appropriate OAuth settings. See Connect to REST-based APIs and Connect to Data 360 Connect API.
To use SOAP API, download a WSDL file and authenticate with a user account. See Connect to SOAP API.